prikaz prve stranice dokumenta "Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."
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undergraduate thesis
"Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."
2023. urn:nbn:hr:155:707380
Brangjolica, Marko
University of Dubrovnik
Department of Applied Ecology

Cite this document

Brangjolica, M. (2023). "Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759." (Undergraduate thesis). Dubrovnik: University of Dubrovnik. Retrieved from https://urn.nsk.hr/urn:nbn:hr:155:707380

Brangjolica, Marko. ""Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."." Undergraduate thesis, University of Dubrovnik, 2023. https://urn.nsk.hr/urn:nbn:hr:155:707380

Brangjolica, Marko. ""Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."." Undergraduate thesis, University of Dubrovnik, 2023. https://urn.nsk.hr/urn:nbn:hr:155:707380

Brangjolica, M. (2023). '"Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."', Undergraduate thesis, University of Dubrovnik, accessed 07 April 2025, https://urn.nsk.hr/urn:nbn:hr:155:707380

Brangjolica M. "Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759." [Undergraduate thesis]. Dubrovnik: University of Dubrovnik; 2023 [cited 2025 April 07] Available at: https://urn.nsk.hr/urn:nbn:hr:155:707380

M. Brangjolica, ""Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."", Undergraduate thesis, University of Dubrovnik, Dubrovnik, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:155:707380

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Metadata
Title"Biomedicinski potencijal obične spužve, Spongia officinalis Linnaeus, 1759."
Title (english)"Biomedical potential of sponge, Spongia officinalis Linnaeus, 1759."
AuthorMarko Brangjolica
MentorSanja Tomšić (mentor)
MentorJosip Mikuš (komentor)
Committee memberSanja Tomšić (predsjednik povjerenstva)
Committee memberMarina Brailo Šćepanović (član povjerenstva)
Committee memberAna Bratoš Cetinić (član povjerenstva)
GranterUniversity of Dubrovnik
(Department of Applied Ecology)
Dubrovnik
Defense date and country2023-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Interdisciplinary Technical Sciences
Abstract
Morski organizmi, većinom beskralježnjaci, zaokupili su pažnju znanstvene zajednice zbog zanimljivih kemijskih spojeva koji imaju specifične biosintetske puteve i fiziološke uloge. Mekušci, spužve, mahovnjaci i drugi organizmi proizvode kemijski vrlo potentne spojeve koji ulaze u medicinsku primjenu kao dodatci postojećim lijekovima ili kao novi lijekovi. Spužve su zaslužne za 30 % od svih dobivenih prirodnih proizvoda iz mora. Farmaceutski interes za spužvama se prvi put javlja prije... More sedamdesetak godina. Obična spužva Spongia officinalis, Linnaeus, 1759 mediteranska je spužva koja je još od antike privlačila pažnju i bila cijenjena u trgovačkim krugovima. Njena je primarna komercijalna upotreba bila za umivanje, a kao i ostale mediteranske spužve ovog roda, koristila se i u razne medicinske svrhe, za ispijanje pića i za nanošenje boje. Danas se provode istraživanja izoliranih sekundarnih metabolita, sintetiziranih posredno u spužvinim stanicama ili neposredno u njenim komenzalističkim mikrobnim zajednicama. Proizvodi dobiveni izolacijom iz raznih spužava pokazuju antiviralno, antitumorsko, antibakterijsko, antifungalno, imunosupresivno, protuupalno, neurološko, bioregenerativno, antidiabetsko i antimalarijsko djelovanje. Dva takva proizvoda, danas priznata terapeutika, Cytarabine i Vidarabine, izolirani su iz karipske spužve Tethya crypta. Spojevi dobiveni iz obične spužve najviše pokazuju antitumorni, potom antibakterijski i neurološki učinak. Uzgoj obične spužve je započeo krajem 18. st. i danas predstavlja alternativu sakupljanju iz prirodnog staništa koji stresira već oštećene populacije. Iako su manje zastupljene u znastvenoj literaturi, mediteranske spužve pokazuju veliki potencijal za razvitak novih biomaterijala s primjenom u biomedicini i drugim industrijama. Less
Abstract (english)
Marine organisms, mostly invertebrates, have captured the attention of the scientific community because of interesting chemical compounds with specific biosynthetic pathways and physiological roles. Molluscs, sponges, bryophytes, and similar organisms produce chemically very potent compounds that enter the medical pipeline as additives to existing or new drugs. Sponges are responsible for 30 % of all natural products obtained from the marine environment. Pharmaceutical interest in... More sponges began about 70 years ago. The bath sponge, Spongia officinalis, is a Mediterranean sponge that has captured attention since antiquity and was valued in commercial circles. Its primary commercial use was for bathing, and like other Mediterranean sponges of this genus, it was also used for various medicinal purposes, for drinking and paint application. Recently, research has shifted focus to isolated secondary metabolites, synthesized directly in sponge cells or indirectly by its commensal microbial communities. Products obtained by isolation from various sponges show antiviral, antitumor, antibacterial, antifungal, immunosuppressive, antiinflammatory, neurological, bioregenerative, antidiabetic, and antimalarial effects. Two such products, nowadays recognized therapeutics, are Cytarabine and Vidarabine isolated from the Caribbean sponge, Tethya crypta. Compounds obtained from bath sponge show mostly antitumor and cytotoxic effects, though antibacterial and neurological activities have been frequently reported in the literature. Cultivation of common sponges began at the end of the 18th century and today stands as an alternative to collection from nature, which stresses already damaged populations. Although they are less represented in the scientific literature, Mediterranean sponges show great potential for the development of new biomaterials with applications in biomedicine and other industries. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:155:707380
Study programmeTitle: /
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a provostupnik/prvostupnica (baccalaures/baccalaurea) inženjer/inženjerka ekologije mora (sveučilišni/a provostupnik/prvostupnica (baccalaures/baccalaurea) inženjer/inženjerka ekologije mora)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2023-12-07 10:53:34
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