The American dermatologist L. Goldman was the first in the field of medicine to use the laser in dermatology. The laser was made of synthetic ruby and Goldman presented its results in 1963. Today, a large number of different lasers are available on the market, for example Q-switcher Nd:YAG, Q-switched ruby laser, Q-switched alexandrite laser, pulsed dye laser, while the old Argon lasers are almost completely out of use. The basic division of lasers includes ablative, non-ablative and fractional lasers. The most common indications for the use of lasers are vascular and pigmented lesions, benign tumors, tattoos, wrinkles, scars and hypertrichosis. Nowadays the use of lasers in the treatment of acne is increasing. The biggest advantage of the laser is the selective removal of changes based on the effects of absorbed laser radiation. The paper describes six devices from polyclinics in the city of Dubrovnik that offer laser treatments. Fractional, diode and Nd:YAG lasers as well as IPL technology are described. The use of the laser is contraindicated at the site of active infection, in pregnant women and patients prone to the formation of keloids and hypertrophic scars, and in certain photosensitive conditions such as lupus and porphyria. The most common side effects include transient edema and erythema at the treatment site that resolve spontaneously within two days. Possible serious side effects include infections, hyperpigmentation, scarring and burns. Before laser treatment, it is necessary to take a detailed history and correctly select the patient for a specific treatment as well as choosing the appropriate settings on the device. During the treatment, it is mandatory to use protective glasses for the patient and the doctor and apply other safety measures.