Title "Cluster glavobolje" Title (english) "Cluster headaches" Author Ivana Kuzman Mentor Denis Čerimagić (mentor)Committee member Dubravka Bartolek Hamp (predsjednik povjerenstva)Committee member Mira Ivanković (član povjerenstva)Committee member Denis Čerimagić (član povjerenstva)Granter University of Dubrovnik Defense date and country 2023-09-07, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract U završnom radu obrađena je tematika cluster glavobolje. Naime, cluster glavobolje su rijetke u usporedbi s drugim vrstama glavobolja. Bol koju proizvode je jaka i svaki put se ponavlja na isti način. Javljaju se u skupinama ili clusterima, a svaki napad u prosjeku traje oko 1 do 3 sata. Učestalost pojavljivanja može varirati od svakog drugog dana do više puta dnevno. Razdoblja clustera slijede remisije koje mogu trajati mjesecima ili godinama. Muškarci su više pogođeni cluster glavoboljama
... More nego žene i obično počinju oko 30. godine. Stručnjaci još uvijek ne znaju puno o cluster glavoboljama, uključujući i što ih točno uzrokuje. Nije jasno što uzrokuje cluster glavobolju. Međutim, smatra se da je povezan s hipotalamusom. Hipotalamus je dio mozga koji je odgovoran za niz tjelesnih funkcija uključujući tjelesnu temperaturu, žeđ, cikluse spavanja, krvni tlak i otkucaje srca. Ne postoji test za cluster glavobolju. Obično će liječnik postaviti dijagnozu prema simptomima i povijesti bolesti glavobolje i obavljanjem neurološkog pregleda. Nažalost, ne postoji lijek za cluster glavobolju. Ali postoji mogućnosti liječenja koje ih mogu učiniti malo manje bolnima, a to su akutno i profilaktičko liječenje, uporaba lijekova te uporaba neurostimulacijskih tehnika. Akutni napadaji cluster glavobolje mogu se zaustaviti liječenjem ili se napadi mogu u potpunosti izbjeći. Najpopularniji tretmani za akutna stanja su kisik i triptani, dok se verapamil i litij koriste kao preventivne mjere. Dokazano je da su kortikosteroidi korisni kada se epizodne cluster glavobolje prvi put pojave dok dugotrajna profilaksa ne postane uspješna. Galcanezumab je pokazao učinkovitost kod bolesnika s epizodnom cluster glavoboljom koji su primali preventivnu terapiju. Liječenje i prevencija također imaju koristi od tehnika neurostimulacije poput invazivne stimulacije okcipitalnog živca i duboke stimulacije mozga, kao i neinvazivne stimulacije živca vagusa i sfenopalatinskog ganglija. Dok preventivno liječenje pokušava smanjiti učestalost i intenzitet napadaja, akutno liječenje cluster glavobolja ima za cilj olakšati simptome i ograničiti vrijeme nelagode. Bolesnici s cluster glavoboljom moraju biti obaviješteni o stanju i o tome kako pravilno koristiti lijekove ako se žele postići željeni terapijski ciljevi. U ovoj situaciji, farmaceuti služe kao poznavaoci veze između liječnika i pacijenata. Less Abstract (english) In the bachelor's thesis, the topic of cluster headaches is discussed. Namely, cluster headaches are rare compared to other types of headaches. The pain they produce is strong and repeats itself every time. They occur in groups or clusters, and each attack lasts about 1 to 3 hours on average. The frequency of occurrence can vary from every other day to several times a day. Cluster periods are followed by remissions that can last months or years. Men are more affected by cluster headaches
... More than women, and they usually start around the age of 30. Experts still don't know much about cluster headaches, including what exactly causes them. It is not clear what causes a cluster headache. However, it is thought to be related to the hypothalamus. The hypothalamus is the part of the brain that is responsible for a number of bodily functions, including body temperature, thirst, sleep cycles, blood pressure, and heart rate. There is no test for cluster headaches. Usually, the doctor will make a diagnosis based on the symptoms and medical history of the headache and by performing a neurological examination. Unfortunately, there is no cure for cluster headaches. But there are treatment options that can make them a little less painful, namely acute and prophylactic treatment, the use of drugs, and the use of neurostimulation techniques. Acute cluster headache attacks can be stopped with treatment, or they can be avoided altogether. The most popular treatments for acute conditions are oxygen and triptans, while verapamil and lithium are used as preventive measures. Corticosteroids have been shown to be useful when episodic cluster headaches first appear and until long-term prophylaxis is successful. Galcanezumab has shown efficacy in patients with episodic cluster headaches receiving preventive therapy. Treatment and prevention also benefit from neurostimulation techniques such as invasive occipital nerve stimulation and deep brain stimulation, as well as noninvasive stimulation of the vagus nerve and sphenopalatine ganglion. While preventive treatment tries to reduce the frequency and intensity of attacks, acute treatment of cluster headaches aims to relieve symptoms and limit the duration of discomfort. Cluster headache patients must be informed about the condition and how to properly use medications if the desired therapeutic goals are to be achieved. In this situation, pharmacists serve as connoisseurs of the connection between doctors and patients. Less Keywords
cluster glavobolja
epidemiologija
dijagnoza
liječenje
Keywords (english)
cluster headache
epidemiology
diagnosis
treatment
Language croatian URN:NBN urn:nbn:hr:155:783315 Study programme Title: Nursing Type of resource Text File origin Born digital Access conditions Access restricted to students and staff of home institution Terms of use Created on 2023-09-14 10:18:28
