A global coronavirus pandemic will certainly leave psychological consequences or has already left them. It is expected that some young people will certainly develop more serious psychological consequences in the form of stress reactions, adjustment disorders or even posttraumatic stress disorder. This is due to fear and exposure to stress due to the uncertainty that has accompanied the growing coronavirus pandemic around the world. Uncertainty is overwhelmed by the flood of bad news (news of the deaths of hundreds of people a day is coming from Europe), while at the same time reducing the seriousness of disinformation from various internet sources that it is a variant of seasonal flu that is dangerous only for the elderly. One of the specifics of the pandemic is isolation and lockdown. State borders are closing, quarantine is often heard in public. Isolation in itself is an unfavorable modality of the functioning of society and civilizations, but also of the individual and the family. Isolation contributes to feelings of fear, especially in those who have previously mentioned risk factors, by increasing uncertainty for the further course of life and existence. According to UNESCO, 1.6 billion students worldwide have been affected by the closure of educational institutions, so there is already talk of a lockdown generation. The COVID-19 pandemic brought a lot of sudden changes in student academic and everyday life to which they had to adapt in a very short time, and with them the negative consequences. This paper aims to determine the impact of lockdown and isolation on the health of young people aged 19 to 28 years.