Lobbying is described as an informal activity aimed at influencing the decision-making process among various levels of government, with the objective of maintaining advantages for specific interest groups. Although lobbying is considered a legitimate practice, there are concerns regarding potential conflicts of interest and undue influence, particularly in countries where legal frameworks, including Croatia, are often lacking. This paper analyzes the role of lobbying in the legalization process of cannabis, especially within the legal and social frameworks of countries such as Croatia, the Netherlands, Germany, Switzerland, and Malta. While concerns exist regarding conflicts of interest associated with lobbying, it can also significantly impact policy formulation, especially in controversial issues like cannabis legalization. The paper emphasizes the health aspects of cannabis use and the importance of achieving a balance between public health protection and commercial pressures. By employing a comparative method, the study will illuminate current legal frameworks and trends in cannabis use, as well as arguments for and against its legalization. Ultimately, the paper highlights how developing a legislative framework for cannabis legalization could yield economic benefits and reduce negative effects associated with the black market. It concludes that lobbying, with appropriate regulations and approaches, can contribute to informed decision-making regarding cannabis legalization.