Management of quality systems is a management function in which work is monitored and measured and corrective actions are taken with the aim of meeting the intended goals of the work organization. In the field of nursing, this is extremely important for the outcomes of overall patient care, which also means ensuring the quality of life of individuals and creating significant savings in the healthcare system. Outcomes of care refer to changes in health status that can be related to everything that was done during the care process. It can be a state of healing, recovery, death or incapacity. This can also include the patient's sense of satisfaction or dissatisfaction (comfort, cleanliness, attitude of the staff towards them...). The term quality management refers to a multidimensional approach to the management of activities to achieve the goals of the work organization, which includes the highest level of process and service excellence and the creation of advantages over other health work organizations engaged in the same work. The quality management system has become more and more complex over time as the requirements of service users have changed. The progress of medicine, technique and technology significantly contributed to changes in the work process, and the need for total quality management (TQM - Total Quality Management) gradually developed. In order to successfully apply this state of mind of the work organization in practice, the work organization must invest in the professional training of its employees, strengthen teamwork and ensure good mutual communication, that is, in the overall organizational culture. Therefore, complete quality management can only be achieved by harmonizing all processes, procedures and interpersonal relationships within the work organization. One of the important parts of quality management is the application of ISO standards. ISO standards standardized the required quality of service and had a significant impact on the quality of services in healthcare. Today, three methods for improving quality are most often used in the world: MBO (Management by Objective), Deming's quality process circle (PDCA / P - Plan (plan), D - Do (do), C - Check and A - Act (Sl) and Six Sigma of quality management Nurses, given their number and the type of work they perform, are the key to quality care and cost management within healthcare institutions that they know very well the strengths and weaknesses of hospital systems and that the largest number participate in the direct process of care, so their role in quality management is immeasurable.