Tourism is the most complex system within the entire economy and as such often affects the development of other branches of economy. In modern times, tourism is one of the fastest growing industries, and it is also the branch that is most sensitive to external factors. Hotel industry as a part of tourism should be able to successfully meet the needs of tourist demand and follow modern trends and adapt to market requirements. It is the hotel chains that are the bearers of standards and quality in the hotel industry and therefore influence the formation of the tourist offer. The final paper analyzes hotel chains, their characteristics and ways of functioning. The aim of this paper is to explore the business of hotel chains on the example of the Sheraton Hotels & Resorts hotel chain and to gain insights into the specifics of the hotel business that is the part of a hotel chain (Sheraton Dubrovnik Riviera Hotel). The characteristics of the business, through the organization of sales, marketing, management, franchising, etc. of the Sheraton Hotels and Resort hotel chain and the business of the Sheraton Dubrovnik Riviera Hotel were analyzed.