The immune system is extremely important for the quality of life of all organisms. It has the ability to recognize pathogens and destroy them, it can also remove its own cells that have started to change. Innate immunity does not require a previous encounter with an antigen for activation, while acquired immunity does. Unlike acquired immunity, innate immunity does not provide long-term immunity against specific antigens. The environment affects immunity every day. Our health is directly related to the environment, various changes can cause a number of health problems such as allergies and heart diseases. The influence of the environment on a certain organism can be studied from several levels, such as global, for example, climate change, to personal, for example, living space. Environmental factors represent a category of immunomodulators that affect susceptibility or resistance to various pathogens. Each organism has adaptations of the immune system to the environment and the opportunities that occur in it.